大语言模型是霍金 Manus 竟成其 “轮椅” KellyOnTech

有没有人跟我一样坐等 Manus 拯救的?邮箱里堆了超过5800封邮件,私信天天爆满,我都感觉自己马上要被这些信息 “淹没”,直接进入想罢工摆烂的状态了。

现在,我已经迫不及待地搓手等待 Manus 的申请码了! 快来拯救我吧,Manus!

2025 年 3 月 6 日,AI 发展迎来重磅时刻 ——Manus 发布!这可是能脱离人工直接指导,独立完成复杂现实任务的自主 AI 代理,由中国初创公司 Monica 打造。

Manus 的名字源自拉丁语“Mens et Manus”(头脑与手),与麻省理工校训不谋而合,象征着创意与执行的完美结合。

“AI 界的六边形战士” 肖弘

提到 Manus 有必要先了解一下被誉为“AI 界的六边形战士” 的创始人肖弘。肖弘虽然是90后,但其实是创业老手,以其卓越的技术能力和商业化经验闻名。

图片来源:新浪科技 Monica 创始人 肖弘

2015 年创立夜莺科技,推出微信公众号运营工具 “壹伴助手” 和 “微伴助手”,服务超 200 万 B 端用户,2020 年项目被某独角兽企业收购。

2022 年他创立 “蝴蝶效应” 公司,推出 AI 浏览器插件 Monica,最初以 ChatGPT for Google 插件形式进入市场,快速积累超 1000 万用户,成为海外头部 AI 助手产品。

Manus 项目最早在2017年上半年开始融资,创始团队以 300万人民币出让10%的股权,但当时许多投资机构并不看好这一项目。然而,肖弘凭借其坚持和创新,最终将 Manus 打造成全球首款通用AI代理产品,重新定义了AI的能力边界。

Manus 到底解决了什么问题

我们常说,认知和见识决定生活的高度。很多人都有目标,比如“今年存一万元去旅游”,但往往缺乏清晰的规划路径。这就是 Manus 的用武之地!

Manus 作为 AI 代理(Agent),它不仅能提供建议,还能独立规划并执行复杂任务,直接交付完整成果。它的强大之处在于:

  1. 连续自主执行:无需反复提示,Manus 可以自主完成任务。
  2. 多任务处理:一次接收一堆任务,甚至能自动解锁压缩包!
  3. 智能拆解与规划:比如,当测试者麻宁让 Manus “给4岁孩子讲清楚伯努利原理”时,Manus 自动拆解任务,生成互动网页,用气球、飞机、泡泡等生活场景辅助理解,还附上了互动小游戏。相比之下,ChatGPT 或 DeepSeek 只能提供文字回答。

技术优势

Manus 采用 Multiple Agent 架构,能在虚拟机中调用多种工具(如编写代码、浏览网页、操作应用等),直接完成任务。在 GAIA 基准测试*中,它的性能甚至超越了 OpenAI的产品。

*GAIA基准测试是一项用于衡量AI代理在无需持续人类指导的情况下,独立规划、执行和完成现实世界任务能力的测试。

Manus比通用大语言模型厉害吗

Manus 和通用大语言模型并不是同一类产品。知名创业者傅盛的观点很有道理,大语言模型,比如 DeepSeek、ChatGPT,是智能的核心,如同拥有深邃思考的大脑。而 Manus 本质上是强化了 AI 的易用性,像是给这个强大的 “大脑” 加了加了一层“外壳”,帮助它与各种网站和工具无缝对接。

打个比方,大语言模型就像《时间简史》的作者、著名物理学家霍金——拥有深邃的思考和理性,却在和世界的互动上存在局限。Manus 就像霍金的轮椅,有了它,霍金才能自如地与外界交流。

A Brief History of Time Stephen Hawking

Manus 的独特之处在于,它将大语言模型的智能转化为实际的行动力,让 AI 不仅会“想”,更会“做”。

Manus 是通用人工智能代理吗

这句话本身值得商榷。大语言模型(如 DeepSeek,ChatGPT)才是“通用”的,而 AI Agent(如 Manus)更像是基于人类经验总结的模板,帮助大语言模型在特定领域增强能力。由于每个领域的模板不同,AI Agent 很难穷尽所有的领域,很难做到真正的“通用”。

畅想一下,未来我们可能会出现各种专用 AI 代理。就像人类虽然智力相近,但通过不同培训形成了不同的专业能力。我个人更加偏向 agent 是专业选手。

关于 Manus,你怎么看?欢迎留言分享!

视频版

English version

Hawking’s Brain Meets Its Wheels: The Big Language Model Meets Manus in a Revolutionary Fusion KellyOnTech

Is anyone else eagerly waiting for Manus to save the day? My inbox is buried under 5,800+ unread emails, and my direct messages are constantly overflowing. I feel like I’m drowning in information and want to go on strike.

Overflowing Emails and DMs

Now, I can’t wait to rub my hands and wait for Manus’s application code! Come and save me, Manus!


 On March 6, 2025, AI development ushered in a major moment — Manus was released! This is an autonomous AI agent that can independently complete complex real-world tasks without direct human guidance. It was created by the Chinese startup Monica. 


The name Manus comes from the Latin “Mens et Manus” (head and hand), which coincides with the motto of MIT, symbolizing the perfect combination of creativity and execution.

Xiao Hong — China’s “Ultimate AI Warrior”

To understand Manus, you first need to know its founder — Xiao Hong, widely recognized as the “Hexagonal Warrior in AI” for his exceptional technical expertise and commercialization skills. 

Image source: Sina Technology Monica Founder Xiao Hong


Born in the 1990s, Xiao Hong is already a seasoned entrepreneur:

2015: Founded Nightingale Technology, launching WeChat tools Yiban Assistant and Weiban Assistant, serving 2M+ business users. The project was later acquired by a unicorn in 2020.

2022: Founded Butterfly Effect and launched the AI browser plug-in Monica — initially a ChatGPT-for-Google tool. It quickly amassed 10M+ users, becoming a top AI assistant worldwide.

Xiao Hong actually started raising funds for Manus back in 2017, selling 10% equity for 3M RMB (USD 410K). At the time, many investors were skeptical. But through persistence and innovation, Manus has emerged as the world’s first general AI agent, redefining what AI can achieve.

What problem does Manus solve?

We often say that your knowledge and vision shape your life. Many people set goals — like saving $10,000 for a trip — but struggle to create a clear, actionable plan. That’s where Manus comes in!

As an AI agent, Manus doesn’t just give advice — it independently plans and executes complex tasks, delivering real results. Here’s what makes it a game-changer:


1. Autonomous Execution — No need for constant prompts. Manus completes tasks independently. 

2. Multitasking Mastery — It can handle multiple tasks at once, even unpacking compressed files automatically. 

3. Smart Task Breakdown — When tester Ma Ning asked Manus to “explain Bernoulli’s principle to a 4-year-old”, Manus didn’t just generate text — it created an interactive webpage with balloons, airplanes, and bubbles, plus mini-games to make learning fun. In contrast, ChatGPT or DeepSeek would only provide a text-based explanation.


Technical Advantages 

 Manus uses a Multiple Agent architecture, leveraging tools like code writing, web browsing, and app operation within a virtual environment to complete tasks. In the GAIA benchmark*, it even performs better than other AI products, such as OpenAI.


* The GAIA benchmark is a test that measures how well an AI agent can plan, execute, and complete real-world tasks independently — without constant human guidance.

Is Manus Better Than General Large Language Models?

Manus and general large language models (LLMs) like DeepSeek and ChatGPT aren’t the same kind of product. 

As serial entrepreneur Fu Sheng aptly puts it, LLMs are the core of intelligence — like a deep-thinking brain. Manus, on the other hand, enhances AI’s usability by adding a “shell” to this powerful brain, enabling it to seamlessly connect with websites, tools, and the real world.

Serial entrepreneur Fu Sheng

Here’s a simple analogy:


 — LLMs are like Stephen Hawking (the famous physicist behind A Brief History of Time) — brilliant, deep thinkers but limited in interacting with the world.
 — Manus is like Hawking’s wheelchair, empowering him to communicate and act freely.

A Brief History of Time Stephen Hawking

What makes Manus unique? It bridges the gap between intelligence and execution, turning AI’s knowledge into action.

Is Manus the World’s First General AI Agent?

This claim is a bit tricky. Large language models (LLMs) like DeepSeek and ChatGPT are “general” by nature, while AI Agents like Manus act more like specialized templates built on human experience, enhancing LLMs’ capabilities in specific areas. Since each field requires different templates, it’s nearly impossible for AI Agents to cover all domains and achieve true “generality.”


In the future, we’ll likely see multiple specialized agents — much like humans, who share similar intelligence but develop unique professional skills through different training. So agents are destined to be experts, not jacks-of-all-trades.


What’s your take on Manus? Share your thoughts below!


For more insights on global cutting-edge tech and innovations, follow “KellyOnTech”!

中文版

Stay Ahead in the AI Age: Unlocking Opportunities with Scenario Maturity

In this era of rapid AI advancement, do you fear being left behind? Today, I’ll introduce a powerful tool — the Scenario Maturity Assessment — to help you stay ahead.


This is my key method for evaluating whether AI-enabled technology companies are worthy of investment. It is not only suitable for entrepreneurs and investors to identify opportunities, but also helps confused parents plan for their children’s future and and take charge in the AI era!

What Is the Scenario Maturity Assessment Method

The concept of scenario maturity was introduced by Zheng Yan, Chief Expert of Huawei Cloud AI Transformation. This framework evaluates opportunities across three critical dimensions:


1. Business Maturity:
A well-defined and stable payer exists.
Clear ownership and accountability are established.
Process rules are transparent and actionable.
User touch points are well-defined and measurable.

2. Data Maturity:
Existing data enables a cold start for the scenario.
Business data flows continuously, updating and generating feedback.
Operations inherently serve as data annotations.
Knowledge data is systematically governed.

3. Technology Maturity:
Existing technology is capable of realizing the scenario effectively.

How to use the Scenario Maturity Assessment Method

The current U.S. President, Donald Trump, once hosted the popular reality show The Apprentice. In its first season, contestants were tasked to sell lemonade. I’ll use this project to demonstrate how the Scenario Maturity Assessment method can be applied.

1. Business Maturity: Can your lemonade business make money?
Is there demand? (Are there thirsty students or office workers nearby?)
Who is in charge? (Are you running it alone or with a team?)
What’s your sales strategy? (Will you set up a stall, push a cart, or use other channels?)
How will customers find you? (Are you located near a bus stop, a school, or another high-traffic area?)

      2. Data maturity: Do you know how to make delicious lemonade?
      Do you have a recipe? (How much lemon and sugar should you use?)
      Are you tracking sales? (How many cups did you sell today? What flavours are most popular?)
      Will you refine it based on feedback? (If customers prefer sweeter lemonade, should you add more sugar?)

        3. Technology Maturity: Do you have the right tools?
        Do you have a juicer? (Or are you squeezing lemons by hand?)
        Do you have a measuring cup? (Or are you eyeballing ingredient proportions?)
        Do you have a cooler? (Or are you selling lemonade at room temperature?)

          By assessing these three areas, you can determine how mature your lemonade business is. The more developed each aspect is, the higher the chances of success!

          Video version

          Scenario Maturity Analysis: Home-Based Elderly Care Humanoid Robot Market

          Let’s use the Scenario Maturity framework to evaluate the home-based elderly care humanoid robot market.

          1. Business Maturity
            Who pays? Who decides?
 Families with elderly care needs are the primary buyers, with purchasing decisions typically made by adult children or the elderly themselves. However, high costs remain a barrier for many families. As technology advances and production scales up, prices are expected to decrease, making these robots more accessible.

          What can robots do?
 Elderly care scenarios are complex and varied, with differences in habits, schedules, and home layouts. Robots currently handle simple tasks like companionship and medication reminders well, but complex tasks (e.g., assisting with bathing or stairs) require further process optimization and safety improvements.
          How do users interact with robots?
Most interactions happen via voice commands or a mobile app, allowing users to check the weather, play music, call family members, or monitor health data. However, voice interaction technology still needs improvement in accuracy and semantic understanding to better meet user expectations.

          1. Data Maturity

          Where does the data come from? 
Currently, data is limited, relying mainly on simulations and small-scale testing, which differ from real home environments. As more robots enter households, they will collect extensive real-world data, such as elderly living habits, health metrics, and interaction records, enabling smarter robot performance.
          How is the data used? 
Robots can track real-time data like heart rate and movement patterns, transmitting it for analysis. This helps detect health issues early and adapt services to better meet the elderly’s needs.
          How is data labeled?
 Each household is unique, making standardized labeling difficult. A flexible framework can allow personalized labeling—tracking task completion, user satisfaction, and care routines to improve robot performance.
          How is data security ensured?
 Elderly care data is sensitive, requiring strict privacy protection. Secure collection, storage, and usage practices must comply with regulations to prevent misuse. Proper data management will also help optimize robot functionality and care services.

          1. Technology Maturity

          What can robots do now?
 They can navigate independently, avoid obstacles, understand basic speech, chat with the elderly, and monitor vital signs like heart rate and blood pressure.
          What are the current limitations?
 Robots still struggle with cluttered home environments, sometimes bumping into objects. They may not understand dialects and cannot perform delicate tasks like dressing or bathing assistance.
          What’s next?
 Future advancements will enhance adaptability, improving sensors and robotic “hands” for greater precision. Robots will work alongside family members and doctors to provide more comprehensive care.
          Interoperability challenges
 Robots need to integrate with smart home and medical devices, but compatibility issues exist due to different standards. Establishing unified protocols will enable seamless communication and better functionality.

          The home-based elderly care robot market holds great potential, but it also faces challenges. Using the Scenario Maturity Assessment framework, we can see that while current robots need improvement in data and technology, advancements and rising demand will drive significant progress.


          This method applies to any industry, offering a structured way to assess its state through three key dimensions:

          1. Business Maturity – driven by demand and regulations.
          2. Data Maturity – shaped by data availability and security.
          3. Technology Maturity – defined by capabilities and innovation

          Whether you’re investing, launching a startup, or planning a career, this framework provides clear insights to help you make informed decisions.

          中文版

          视频版

          AI 赋能时代 “场景成熟度”助你洞察先机

          在如今这个 AI 疯狂发展的时代,你是否担心在 AI 浪潮中被淘汰,成为时代的“韭菜”?今天我分享一个实用的“指南针”——场景成熟度评估法

          这是我评估 AI 赋能的科技公司是否值得投资的核心方法,它不仅适用于创业者投资人甄别机会,更能帮助迷茫的家长为孩子规划未来,在AI时代抢占先机!

          什么是场景成熟度

          场景成熟度这一概念,由华为云 AI 变革首席专家郑岩提出。评估场景成熟度主要涵盖以下三个方面:

          1. 业务成熟度 — 有清晰稳定的付款方,有清晰明确的责任人,明确的流程规则,明确的用户触点
          2. 数据成熟度 — 已有数据支持冷启动,业务数据随作业持续,产生更新和反馈,作业即标注,知识数据的治理
          3. 技术成熟度 — 现有技术支撑场景实现

          如何使用场景成熟度评估法

          现任美国总统 Donald Trump 曾搞过一档超火的真人秀招聘节目《The Apprentice》(学徒)。第一季里有个考核是让选手们摆摊卖柠檬水,我就用这个项目举例说明如何应用场景成熟度评估法。

          1.业务成熟度:你的柠檬水摊能赚钱吗?

              有没有人愿意付钱? (比如,附近有没有口渴的学生,上班族?)

              谁来负责? (是你自己,还是和其他人一起合作?)

              怎么卖? (是摆个摊子,还是推着小车到处走?还是通过其他渠道卖?)

              顾客怎么找到你? (是在车站,还是在学校附近?)

              2. 数据成熟度:你知道怎么做出好喝的柠檬水吗?

              你有配方吗? (比如,知道要放多少柠檬和糖?)

              你会记录每次卖的情况吗? (比如,今天卖了多少杯,顾客喜欢什么口味?)

              你会根据顾客的反馈改进配方吗? (比如,下次多放点糖?)

              3. 技术成熟度:你有工具做出好喝的柠檬水吗?

              你有榨汁机吗? (还是只能用手挤柠檬?)

              你有量杯吗? (还是只能凭感觉调配糖和柠檬水的含量?)

              你有保温箱吗? (还是只能卖常温的柠檬水?)

              通过这三个方面判断,场景成熟度越高,摆摊卖柠檬水的项目就越容易成功。

              居家养老人形机器人市场:场景成熟度分析

              好,我们用场景成熟度分析一下居家养老人形机器人处于什么阶段。

              1. 业务成熟度

              谁买单?谁做主?想买养老机器人的,大多是有养老需求的家庭,做购买决定的一般是家里的成年子女或者老人自己。不过现在这机器人价格挺贵,好多家庭买不起。随着技术进步和规模化生产,成本有望降低,使更多家庭能够负担得起。

              机器人能干啥?家庭养老场景复杂多样,每个家庭的生活习惯、作息时间、房屋布局等都有所不同,缺乏统一标准流程。目前,机器人在简单的陪伴聊天、提醒吃药等任务上有一定成熟度,但在协助老人洗澡、上下楼梯等复杂且具有一定危险性的任务方面,还需要进一步优化流程和提高安全性。

              和机器人咋互动?用户主要通过语音交互、手机 APP 等方式与人形机器人互动。用户可以用简单语音指令让机器人做事,比如如查询天气、播放音乐、呼叫家人等,同时也能通过 APP 设置机器人的工作模式、查看老人的健康数据等。当前,语音交互技术在准确性和语义理解上仍有提升空间,以更好地满足用户的需求。

              1. 数据成熟度

              数据从哪里来?目前数据不多,主要靠模拟和少量测试,跟真实家庭情况有差距。未来更多机器人进入家庭后,会收集大量真实数据,比如老人生活习惯、健康状况、与机器人互动记录等,帮助机器人变得更聪明。

              数据怎么用?机器人能实时收集老人数据,比如心跳、活动轨迹等,并传回后台分析。通过分析数据,可以及时发现老人健康问题和生活需求,调整机器人服务。

              数据怎么标注?每个家庭情况不同,很难统一标注标准。可以建立通用标注框架,结合家庭特点进行个性化标注,比如记录护理任务完成情况和老人满意度,帮助改进机器人性能。

              数据安全怎么保障?老人数据涉及隐私,必须建立完善的数据保护体系。确保数据采集、存储、传输和使用都合法合规,防止泄露和滥用。同时要有效管理和分析数据,提取有用信息,帮助优化机器人和提升养老服务。

              3. 技术成熟度

              机器人现在能干啥?能自己走动,避开家具和墙壁。能听懂简单的话,跟老人聊天。能测心跳、血压,看老人活动情况。

              但还不够好:家里东西多,机器人有时会撞到。老人说话有方言,机器人不一定听得懂。帮老人穿衣服、洗澡这些精细活,机器人还干不了。

              未来会更好:科学家们正在研究新技术,让机器人更聪明,能适应不同家庭和老人需求。开发更好的传感器和“手”,让机器人感知更灵敏,干活更灵活。让机器人和家人、医生一起照顾老人,提供更全面的服务。

              机器人要跟其他设备“交朋友”:机器人需要跟家里的智能设备、医疗设备连接,共享信息。但现在不同品牌的设备之间“语言不通”,需要制定统一标准,让它们更好地合作。

              居家养老机器人市场潜力巨大,但挑战与机遇并存。通过“场景成熟度评估法”,我们可以清晰地看到,尽管当前机器人在数据积累、技术成熟度等方面仍有提升空间,但随着技术进步和市场需求增长,未来前景广阔。

              无论什么行业,你都可以通过场景成熟度评估法从业务、数据、技术三个维度,快速解析行业现状。业务成熟度看需求与规范,数据成熟度看数据积累与数据安全,技术成熟度看能力与发展。无论是投资、创业还是职业规划,这一方法都能提供为你提供清晰的指引,助你做出更明智的决策。

              视频版

              再不了解 AI 时代真正核心,你将被时代狠狠甩下!

              我们正站在一个时代的十字路口,人工智能不再是科幻小说里的幻想,它已经渗透进我们生活的方方面面,悄然改变着游戏规则。

              人工智能时代,什么才是真正的核心竞争力?

              AI 时代的核心是什么?

              是数据?算法?还是计算能力?虽然这些要素必不可少,但它们并不是人工智能时代的真正核心。真正改变游戏规则的是决策质量。

              人工智能啥时候入了政府的 “法眼” 呢?以前,就算 2015 年微软算法让 AI 识别猫的准确率飙到 96%,把人类远远甩在身后,各国政府还是没把 AI 当回事儿。

              围棋之战:AI决策的巅峰对决

              还记得2016年那场轰动全球的围棋比赛吗?谷歌的AlphaGo对阵人类顶尖棋手李世石。从那以后,人类再未在围棋领域战胜过人工智能。

              AlphaGo 为啥能赢?每下一步棋,都是在做决策。AI 不仅能计算眼前的局面,还能预测未来的几十步甚至上百步。

              人类棋手靠经验和现场反应,而AI靠的是精确的计算和不断优化的策略。这场对决不仅是围棋的胜负,更是决策质量的革命。

              最早意识到事情真正重要性的是中国政府,2017年,印发《新一代人工智能发展规划》,宣布要“到2030年人工智能理论、技术与应用总体达到世界领先水平,成为世界主要人工智能创新中心”。

              自动驾驶:AI 决策的现实应用


              AI 决策质量的提升不仅体现在棋盘上,更体现在我们的日常生活中。自动驾驶就是最好的例子。

              自动驾驶的核心是什么?是感知系统和决策系统的完美结合。

              人类驾驶的局限:我们靠眼睛观察路况,但视野有限,盲区常有;靠耳朵听声音,但车内音乐、车外噪音常常让我们分心。更重要的是,人类的学习能力有限。一旦学会开车,很少有人会不断优化自己的驾驶技术。疲劳驾驶、情绪波动(比如“路怒症”)更是让驾驶风险倍增。

              AI驾驶的优势:相比之下,AI驱动的汽车搭载了多个摄像头、雷达和传感器,能够360度无死角感知周围环境。它不会分心,不会疲劳,更不会路怒。通过不断学习和优化,AI终将能够轻松应对复杂的道路环境,安全驾驶率不断提升,最终超越人类。

              所以,AI 时代的核心,正是决策质量的不断提升。从围棋棋盘上的步步为营,到自动驾驶汽车在复杂路况中的游刃有余,AI 正以更高效、更精准的决策改变着世界的运行方式。

              当 AI 决策逐渐渗透生活的每一个角落,我们又该如何在这浪潮中找准自己的位置,在这场由AI 引领的决策革命中,你,准备好了吗?

              视频版

              English version

              六道题看穿你的抗老潜力:压力正悄悄 “剪短” 你的端粒 KellyOnTech

              上期介绍了亿万富翁和超模们的逆龄密码:端粒的奥秘

              我们已经了解端粒长度,作为衡量衰老进程与细胞健康状况的关键生物标志物,其重要性不言而喻。研究表明,端粒越短,机体越易受衰老相关疾病侵扰。同时,长期压力以及不良生活方式,像不合理饮食、运动量匮乏等,也都与端粒缩短有着千丝万缕的联系。

              市面上延长端粒的产品要么还在试验阶段,要么价格不菲。这期就介绍一个自测你的抗衰老能力,看看压力是否损坏了自身端粒健康的测试。它由 2009 年的诺贝尔奖获得者 Dr. Elizabeth Balckburn 提出。特别指出,这项测试不是诊断量表,旨在提高你对以某种方式应对慢性压力的倾向的认识。

              六道题看穿你的抗老潜力

              首先想一个在你现在的生活中让你非常困扰的情况,选出你对每个问题的答案,总共六题。待你选定答案后,我会详细阐述每道题目背后所考查的要点。

              1. 当你考虑如何应对这种情况时,你感到的希望和信心与恐惧和焦虑相比有多大?( 0 – 4 分)

              0 充满希望、信心 2 各有一定程度 4 恐惧、焦虑

              1. 你是否觉得自己拥有有效应对这种情况所需的一切?( 0 – 4 分)

              4 完全没有 3 2 有点 1 0 拥有所需的一切

              1. 你对这种情况的反复思考有多深?( 0 – 4 分)

              0 完全没有 1 2 有点 3 4 非常深

              1. 你在多大程度上避免考虑这种情况或尽量不表达负面情绪?( 0 – 4 分)

              0 完全没有 1 2 有点 3 4 尽量避免

              1. 这种情况让你对自己感觉有多糟糕?( 0 – 4 分)

              0 完全没有 1 2 有点 3 4 非常糟糕

              1. 你在多大程度上以积极的方式看待这种情况,看到可能从中产生的一些好处,或者告诉自己一些让你感到安慰或有帮助的话,例如你正在尽最大努力?( 0 – 4 分)

              4 一点也不积极 3 2 有点 1 0 非常积极

              面对压力,你的应对方式是 “抗老能手” 还是 “抗老杀手”

              现在开始计算你的总分,请将所有数字相加。

              如果你的测试总分在 11 分及以下,那恭喜你,你的压力应对风格相当健康。面对压力,你不会轻易被其威慑,反而更倾向于将它视作挑战,还能巧妙地限制压力对生活其他方面的影响。

              压力事件过后,你也能迅速调整状态,快速恢复过来。这种强大的压力恢复能力,对维持端粒的健康非常有利,意味着你的身体细胞衰老速度可能会更慢,健康更有保障。

              要是你的总分达到了 12 分及以上,别担心,你和很多人一样。在压力环境中,由于个人思维习惯的影响,你感受到的威胁会被放大。

              而这些习惯,无论是直接作用还是间接影响,都与端粒缩短脱不了干系,可能会在不知不觉中加快身体的衰老进程,所以需要多多留意并尝试改善 。

              每道题目背后,究竟在考查什么要点

              问题一和问题二,主要考察的是一种思维习惯,它们能够衡量出你在面对压力时,感受到的威胁程度究竟有多高。

              当你内心充满高度恐惧,且自己感觉所需资源严重不足时,身体就会引发强烈的荷尔蒙变化,炎症应激反应也会随之而来。这种被视作威胁的压力,会触发一系列心理和生理反应,要是长期处于这种状态,日积月累,你的端粒可就要遭殃了。

              问题三主要评估你的思维模式是否倾向于过度反刍。反刍思维是指对困扰你的事情进行反复、无效的思考。如果你不确定自己是否有这种倾向,现在就可以开始留意了。

              大多数压力源其实是短暂的,但我们人类有一种特殊的能力——让这些压力在脑海中反复重现,甚至在事情过去很久后仍然挥之不去。这种反刍思维可能会演变成更严重的状态,比如抑郁性反刍,表现为对自己和未来的消极想法。这种思维模式是有害的,因为它会消耗大量时间和精力,让你不断重复那些已经过去的事情,而忽略了改善生活的机会。

              问题四,主要考察的是你在面对压力时,是否存在回避和压抑情绪的倾向。仔细想想,当遇到压力状况,你会不会下意识地不去思考它,或者哪怕心里憋闷,也不愿跟人分享自己的感受?是不是有些压力让你感觉太过沉重,只要一回想起来,胃就会不自觉地揪紧,仿佛有块大石头压着?

              其实,想要躲开那些难受的感觉,这是人之常情,大家都会有这样的本能。在刚面对压力的时候,这种回避策略或许能让你心里好受点,可要是压力一直持续,问题始终没有解决,它就没什么用了,甚至还可能让负面情绪在心里越积越多,憋出更大的问题。

              问题五聚焦于我们在压力情境下的自我威胁意识。当面临棘手的压力状况且事情进展不如人意时,不妨问问自己,是否会感觉自尊心受挫,甚至开始怀疑自己的个人价值与身份认同?压力是否会促使你产生一系列诸如 “我怎么这么没用” 的负面自我评价,让你觉得自己仿佛一文不值?

              偶尔产生这类自我批评的念头,其实是很正常的,毕竟谁都有状态不好的时候。但倘若这些想法频繁冒出来,就像阴魂不散的乌云,时刻笼罩着你,那可就麻烦了。它们会使你的身体陷入一种过度敏感、反应过激的状态,而压力荷尔蒙皮质醇水平升高,就是这种糟糕状态的典型表现。

              问题六,主要探讨的是你在面对压力时,是否具备积极重新评估的思维习惯。简单来说,就是当你身处压力情境之中,能不能换个角度,用积极的心态去重新审视这件事。具备这种能力,你就能把看似不利的状况转化为自身优势,就算做不到这一点,也至少能减轻它带来的痛苦。

              此外,这个问题还会考量你是否懂得给予自己健康的自我同情。当压力来袭,你能否以温和、理解的态度对待自己,而不是一味地苛责,这也是积极应对压力的重要一环。

              好了,现在你自测了自己抗衰老的潜力,和应对压力的模式。过大的压力会加速端粒缩短,让衰老的脚步更快。那怎么办呢?别着急,在接下来的这一年里,我会向你分享一系列实用方法,教你如何改变那些不利于端粒健康的习惯,或者最大程度减轻它们对端粒以及衰老进程的负面影响,帮你重拾健康生活节奏,守护身体的年轻态。

              视频版

              亿万富豪和超模的 “逆龄密码”:端粒如何重塑生命长度 KellyOnTech

              亿万富翁比如 Jeff Bezos、Sam Altman、Peter Thiel 与超模 Veronica Webb、Kate Moss 等等之间,究竟藏着怎样意想不到的交集?

              他们都将目光投向了抗衰老与长寿领域的研究,纷纷投资相关公司。而超模们也对端粒修复产品情有独钟,近乎痴迷。2025年乙巳蛇年已至,在这个万象更新的年度里,我们一起解锁端粒的奥秘。

              为什么说理论上讲人可以活到120岁?

              端粒(Telomere)是染色体末端的保护帽,帮助细胞保持健康,由重复的 DNA 序列和相关蛋白组成。

              为了更直观地理解,不妨想象一下鞋带。端粒就像鞋带末端的塑料套,看似毫不起眼,却默默守护着鞋带的完整性,保护我们的 DNA 不受损坏或纠缠。细胞每一次分裂,就如同鞋带在日常使用中不断受到摩擦,端粒也会随之逐渐变短,恰似塑料套慢慢磨损。当塑料套被磨没了,鞋带就会从末端散开,直到没法用了。同理,随着时间的推移,当端粒变得太短时,细胞就无法正常工作。端粒与衰老和某些疾病的产生有着千丝万缕的联系。

              端粒示意图

              当我们出生的时候,在每个干细胞里,大约有5000-6000个端粒,而科学家测算过,端粒从开始磨损直至耗尽的时间大约为 120 年。这一科学发现,也正是 “人理论上可以活到 120 岁” 这一说法的重要计算依据。

              如何延缓端粒的衰退?

              如何有效延缓端粒衰退,成为了科学界与追求健康长寿人群密切关注的焦点。

              端粒长度,作为衡量衰老进程与细胞健康状况的关键生物标志物,其重要性不言而喻。研究表明,端粒越短,机体与衰老相关疾病的距离就越近,同时,长期压力以及不良生活方式,像不合理饮食、运动量匮乏等,也都与端粒缩短有着千丝万缕的联系。

              虽然端粒会随着时间的推移逐渐变短,最终导致细胞衰老和死亡,但是某些细胞(如干细胞和癌细胞)可以借助一种名为端粒酶(Telomerase)的酶来延长端粒长度,维持细胞的持续分裂能力,从而延缓衰老进程。

              市面上有延长端粒长度来抗衰老的产品吗?

              在追求青春永驻、对抗衰老的漫漫长路上,无数人都在翘首以盼,市面上究竟有没有能够通过延长端粒长度来实现抗衰老的神奇产品呢?

              截至目前,这类旨在延长端粒长度以达到抗衰目的的产品,依旧处于紧锣密鼓的试验阶段。不过,一款名为 Telomir-1 的产品,已在业界成功吸引了众多目光,成为众人瞩目的焦点。它是由专注于抗衰老科学研究,并在纳斯达克上市的制药公司 Telomir Pharmaceuticals, Inc. 精心研发的新型小分子,其核心使命便是延长端粒长度。2024 年 11 月,Telomir 公司公布了具有开创性意义的临床前研究结果,这一成果令人振奋不已,不仅证实了 Telomir-1 具备延长生物体寿命的潜力,更惊喜地发现它还能显著改善健康寿命,让生命在更长的时间里保持良好状态。

              据该公司介绍,Telomir-1 从最初的小鼠试验,到后续在狗身上展开的深入研究,再到如今的人体细胞试验,一路表现出色,成果斐然。在实验数据中,它能够将人体干细胞里的端粒含量提升 10 倍之多。以年老的狗为例,原本其干细胞中仅有 300 个端粒,经过 Telomir-1 的作用后,端粒数量飙升至 3000 个,从外观上看,狗的面貌焕然一新,姿态也变得更加矫健,全身仿佛重新焕发了生机,活力满满。

              尽管目前这项技术还处于临床试验阶段,尚未完全成熟,但它无疑为人类在抗衰老领域的探索,点燃了一盏全新的希望之灯。遥想古今中外,上至帝王将相,下至普通百姓,无不对返老还童的美好愿景充满向往,或许在不久的将来,这一曾经只存在于幻想中的场景,真的会成为现实,让我们共同满怀期待,拭目以待。

              值得特别强调的是,Telomir-1 这款神奇的药物,其应用价值远不止于抗衰老。它还在医疗领域展现出了巨大的潜力,有望用于治疗早衰症、2 型糖尿病,以及一系列与衰老密切相关的疾病,如阿尔茨海默病、某些类型的癌症、威尔逊病和骨关节炎等。这意味着,它不仅可能改写人类对抗衰老的历史,还将为众多患者带来战胜疾病的曙光,助力医学发展迈向新的里程碑。

              视频版

              Understand the Core of the AI Era—Or Get Left Behind!

              What Defines the AI Era?

              Is it data? Algorithms? Computing power? While these elements are essential, they are not the true core of the AI era. The real game-changer is decision quality.

              AI has transitioned from the lab to the real world not just because it can process vast amounts of data or execute complex calculations, but because it has fundamentally improved the way decisions are made. This leap in decision-making capability is what’s reshaping industries, transforming our daily lives, and defining the future of technology.


              Go Battle: The Pinnacle of AI Decision-Making

              Remember the Go* match that shocked the world in 2016? AlphaGo played against the top human player Lee Sedol. Since then, no human has ever defeated AI in the world of Go. AlphaGo’s victory is not accidental. Every move it made was a carefully calculated decision. Unlike human players, who rely on intuition, experience, and real-time judgment, AI evaluates countless possibilities, predicting dozens — or even hundreds — of moves ahead. This duel was more than the victory or defeat of a Go game; it marked a revolution in decision-making itself.

              *Go, an ancient Chinese strategy game is played with black and white stones, where the player who controls the most territory wins. Known as the “King of Board Games,” it embodies art, wisdom, and deep philosophy.

              Autonomous Driving: AI Decision-Making in the Real World

              The improvement in the quality of AI decision-making is not only reflected on the chessboard but also in our daily lives. Autonomous driving is one of the best examples.

              What is the core of autonomous driving? It is the perfect fusion of perception and decision-making.

              The limitations of human driving: Humans rely on our eyes to navigate the road, but our field of vision is limited and blind spots are unavoidable. We use our ears to detect sounds, yet distractions — music, conversations, or outside noise — often distract us. More critically, human learning is finite. Once we learn to drive, few of us refine our driving skills further. Fatigue, stress, and emotions like road rage further increase accident risks.

              Advantages of AI driving: In contrast, AI-driven cars are equipped with multiple cameras, radars and sensors that provide a 360-degree view of the surrounding environment without blind spots. AI doesn’t get distracted, fatigued, or emotional. Unlike humans, it learns and optimizes continuously, adapting to complex road conditions, and improving safety over time. Eventually, AI-driven cars will surpass human drivers in reliability and efficiency.

              From the strategic brilliance of Go to the precision of autonomous vehicles, AI is changing the way the world works with more efficient and accurate decisions. AI is transforming decision-making across every domain. As AI systems become more advanced, making faster and more accurate choices than ever before, they are redefining how the world operates. 

              As AI decision-making seeps into every corner of life, the real question is: How can we find our place in this wave? In this AI-driven revolution, are you ready?

              Special Notes

              Over the past 20 years, I have had the privilege of working with founders, investors, and technical teams from technology companies worldwide, particularly in China, the United States, Canada, Singapore, the United Kingdom, the Netherlands, Germany, Japan, and beyond. Given the diverse national and cultural backgrounds, misunderstandings are sometimes inevitable, especially when it comes to perceptions of China.

              To bridge this gap, starting this year, I have decided to regularly share insights from thought leaders in China’s tech industry, offering cutting-edge perspectives and unique viewpoints.

              My aim is to foster deeper mutual understanding and break down unnecessary barriers. After all, in an era of rapid AI advancements, humanity must work together to navigate the complexities of intelligent technologies and jointly build a brighter future.

              Liang Ning Introduction

              The above content is compiled based on Liang Ning’s understanding of the AI era.

              Liang Ning is an outstanding business thinker in China’s technology field. In her 20s, she worked with Academician Ni Guangnan to develop China’s domestic chips and operating systems. Later, she founded a well-known outdoor travel portal, Green Man. After the website was acquired by Tencent, she served as Tencent’s product manager. After leaving in 2014, she focused on in-depth research of enterprises.

              Video version

              中文版视频

              中文版

              2025 破什么会让你的心态超越99%的同龄人

              2025年破什么会让你的心态超越99%的同龄人?

              2025破什么会让你的心态超 KellyOnTech

              于我而言,是破我执。

              本科学哲学的黄子华是我喜欢的香港演员之一,由他领衔主演的电影 《破地狱》以香港殡葬行业为蓝本,讲述死亡这一深刻话题。

               

              “破地狱” 起初是香港道家超渡亡灵的传统仪式,现今已作为一项殡葬仪式被纳入中国非物质文化遗产名录。

              影片中给我印象最深刻的故事是一位母亲,在儿子离世半年后,仍然舍不得将其下葬。她对儿子的爱无比执着,跨越生死,让人唏嘘。有别于取走内脏再制作木乃伊的做法,她一心想要完整地保留儿子的遗体,满心期待着在未来科技昌明之时,或许可以盼来儿子的起死回生。

              “破地狱”,其本意乃在于打破地狱对亡者的禁锢枷锁,然而殊不知,在世之人亦亟需一场心灵的 “超渡”。尘世之中仿若存有 “地狱”,那便是深植于我们内心的诸般执念。你我皆为尘世凡人,各自怀揣着形形色色的执念。“退一步海阔天空” 之语,我们已然听闻过太多回,可每每身处具体情境之中,却常常难以释怀,不愿放下执念,去冲破那禁锢心灵的牢笼。

              对于死亡,人皆向死而生,就像搭乘人生列车,到站了就下车,仿若雁过无痕,不着于念。

              境随心转,当心境转变,周遭万物亦随之而变。无论将其视作认知与格局的提升,还是能量场的进阶,摆脱我执也罢,一切都会过去的。

              心有不甘时,便竭尽所能做好分内之事,其余种种,皆交付于岁月洪流,毕竟执着于不可控之事,终是徒劳无益。

              在那部剧中,与黄子华相伴多年的女友怀孕了,黄子华起初并并不愿迎接这个新生命的降临,他的理由是他已经五十多岁了,他担忧当自己好不容易与孩子建立起深厚情感,孩子正值青春韶华之际,他却不得不面对生命的终结,如此场景是他所不愿面对的。

              不知是否有朋友和我一样,对福宝熊猫情有独钟?姜爷爷和宋爷爷早在福宝出生那天就知道,福宝长大了要回归祖国,但这丝毫未减损他们给予福宝的疼爱与关怀。在相伴的时光里,他们全心付出爱意,尽情品味着相处的温馨与美好。

              Fubao Panda 福宝熊猫

              其实即便心怀 “我执”,也可以尽情体验和享受这来之不易的人生旅程,哪怕生命从一开始便似进入倒计时,又有何妨?就如张曼玉所言:“我的人生,我来创造。” 

              2025 年乙巳蛇年,让我们满怀期待地奔赴新程!

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              2025年你准备以什么样的心态度过? 获许可以从你的AI 小助手为你选的书里找到答案

              2025年你读的第一本书是什么?如果没感觉,不妨问问自己的人工智能小助手。

              我的 AI 小助手帮我选的是法国作家阿尔贝·加缪创作的哲学随笔《西西弗斯神话》。

              在希腊神话中,西西弗斯(Sisyphus)是风神埃俄罗斯(Aeolus)之子。他因触怒宙斯(Zeus),受到惩罚,需要每天将巨石推往山顶,可巨石每次刚到山顶,便不受控制地滚落下来,如此循环往复,周而复始。

              按理来说这般单调无聊、永无止境且毫无成就感的苦役,西西弗斯应该陷入巨大的绝望中。

              然而,有一天当西西弗斯下山准备再次推动巨石时,路过的爱神(Aphrodite)却见他笑容满面,神采奕奕。不禁感到十分诧异,于是问道:“你做着这么无聊的事情,为何还能如此高兴?”

              西西弗斯兴奋地指着手中的花朵,向爱神展示着自己的意外收获:“你看,我在山腰处发现了这朵美丽无比的花。”

              西西弗斯日复一日地推着那块永远无法静止的巨石是徒劳的,但他因此走过的山路,采过的鲜花,还有呼吸到的山间清新的空气,无一不是真实可触的自然馈赠,绝非徒劳。

              生活何尝不是如此?本就是由日常的点点滴滴汇聚而成,我们的喜怒哀乐,酸甜苦辣相互交融,沾满了柴米油盐的烟火气和各种琐碎细微的瞬间。如果我们一心只盯着遥不可及的目标,一路狂奔,很容易忽略沿途那些悄然绽放的小小的美好。

              所以,在2025年,不妨用心体悟每一个当下,主动营造一种内在的宁静。不要错过那些只属于我们自己的无数个小小的惊喜。2025年让我们的心变得柔软而敏感,适当放下对周围的一些不必要的戒备,让心灵变得柔软和充满爱意,尽情拥抱生活的每一面。让我们一起淡定、从容地生活!

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